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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AURKA
All Species:
10.3
Human Site:
T95
Identified Species:
15.11
UniProt:
O14965
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14965
NP_003591.2
403
45809
T95
V
S
R
P
L
N
N
T
Q
K
S
K
Q
P
L
Chimpanzee
Pan troglodytes
XP_525364
403
45791
T95
V
S
R
P
L
N
N
T
Q
K
S
K
Q
P
L
Rhesus Macaque
Macaca mulatta
XP_001098364
471
52859
P162
S
A
P
S
P
L
L
P
M
S
S
P
K
A
A
Dog
Lupus familis
XP_853397
405
45606
T96
A
S
R
S
L
N
N
T
Q
K
S
E
Q
P
S
Cat
Felis silvestris
Mouse
Mus musculus
P97477
395
44754
A95
P
Q
K
N
E
Q
P
A
A
S
G
N
D
S
E
Rat
Rattus norvegicus
P59241
397
44856
Q95
P
Q
K
S
E
Q
P
Q
P
A
A
S
G
N
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521399
303
34973
S28
E
S
K
K
R
Q
W
S
L
D
D
F
D
I
G
Chicken
Gallus gallus
XP_425725
409
46456
P99
P
T
A
G
P
Q
V
P
S
K
N
S
E
K
P
Frog
Xenopus laevis
Q91819
408
46443
N97
K
P
Q
G
P
N
E
N
R
N
P
Q
Q
T
S
Zebra Danio
Brachydanio rerio
Q6NW76
320
36928
S45
R
V
P
V
K
S
N
S
K
V
L
S
I
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKN7
329
38282
F53
Y
D
W
S
P
R
D
F
E
M
G
A
H
L
G
Honey Bee
Apis mellifera
XP_395732
327
37711
K52
E
Q
N
I
T
N
N
K
K
Q
T
D
K
K
W
Nematode Worm
Caenorhab. elegans
O01427
305
34731
F30
G
K
F
T
I
N
D
F
E
I
G
R
P
L
G
Sea Urchin
Strong. purpuratus
XP_001181990
278
32048
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q683C9
282
32738
Baker's Yeast
Sacchar. cerevisiae
P38991
367
42927
K92
K
M
I
H
E
N
K
K
L
P
K
F
K
S
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
47.7
89.8
N.A.
82.6
83.6
N.A.
65.5
73.1
65.9
53.3
N.A.
38.4
53
46.6
50.6
Protein Similarity:
100
100
62.2
93
N.A.
86.8
87.3
N.A.
70.2
82.8
77.2
65.7
N.A.
57.8
67
56.3
60
P-Site Identity:
100
100
6.6
73.3
N.A.
0
0
N.A.
6.6
6.6
13.3
6.6
N.A.
0
13.3
6.6
0
P-Site Similarity:
100
100
20
80
N.A.
6.6
13.3
N.A.
20
26.6
33.3
26.6
N.A.
13.3
40
33.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
46.4
38.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.3
57.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
0
0
0
0
7
7
7
7
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
13
0
0
7
7
7
13
7
7
% D
% Glu:
13
0
0
0
19
0
7
0
13
0
0
7
7
0
7
% E
% Phe:
0
0
7
0
0
0
0
13
0
0
0
13
0
0
0
% F
% Gly:
7
0
0
13
0
0
0
0
0
0
19
0
7
0
19
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
7
7
7
0
0
0
0
7
0
0
7
7
0
% I
% Lys:
13
7
19
7
7
0
7
13
13
25
7
13
19
13
0
% K
% Leu:
0
0
0
0
19
7
7
0
13
0
7
0
0
13
19
% L
% Met:
0
7
0
0
0
0
0
0
7
7
0
0
0
0
0
% M
% Asn:
0
0
7
7
0
44
32
7
0
7
7
7
0
7
7
% N
% Pro:
19
7
13
13
25
0
13
13
7
7
7
7
7
19
7
% P
% Gln:
0
19
7
0
0
25
0
7
19
7
0
7
25
0
0
% Q
% Arg:
7
0
19
0
7
7
0
0
7
0
0
7
0
0
0
% R
% Ser:
7
25
0
25
0
7
0
13
7
13
25
19
0
13
13
% S
% Thr:
0
7
0
7
7
0
0
19
0
0
7
0
0
7
0
% T
% Val:
13
7
0
7
0
0
7
0
0
7
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
7
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _